Novel Strategies for Anterior Segment Ocular Drug Delivery
نویسندگان
چکیده
منابع مشابه
Ocular Iontophoresis for Anterior and Posterior Segment Drug Delivery
Over the recent decades, there has been seismic shift in the field of ocular drug delivery ranging from dosage form design to drug product commercialization. Advancements in the fields of nanotechnology, biomedical engineering and clinical science significantly improved the feasibility of ocular drug delivery. Despite these technological advances, there exists need to deliver drugs in therapeut...
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Ocular drug delivery is challenging due to the presence of anatomical and physiological barriers. These barriers can affect drug entry into the eye following multiple routes of administration (e.g., topical, systemic, and injectable). Topical administration in the form of eye drops is preferred for treating anterior segment diseases, as it is convenient and provides local delivery of drugs. Maj...
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One inch or less. That is the short distance an ocular drug must travel to reach a target site at the back of the eye. Research has come a long way over the past 4 decades in efforts to make this inch-long journey more successful. Delivering ocular drugs to their target tissues often requires them to traverse the fat-water-fat structure of the corneal barrier while ensuring minimum wastage thro...
متن کاملOcular Drug Delivery: Targeting the Posterior Segment
An inch or less. That is the short distance an ocular drug must travel to reach a target site at the back of the eye. Research has traveled a long way over the past 4 decades in efforts to make this inch-long journey more successful. Delivering ocular drugs to their target tissues often requires them to traverse the fatwater-fat structure of the corneal barrier, while ensuring minimum wastage t...
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Eye is the most vital organ of the body. To achieve effective ocular therapy, an adequate amount of active ingredients must be delivered and maintain at the site of action within the eye. The anatomical structure and the protective physiological process of the eye exert a formidable defense against ophthalmic drug delivery, leads to poor precorneal drug loss results in poor ocular by availabili...
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ژورنال
عنوان ژورنال: Journal of Ocular Pharmacology and Therapeutics
سال: 2013
ISSN: 1080-7683,1557-7732
DOI: 10.1089/jop.2012.0200